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Future Treatments and Research for Hyperhidrosis
Written by Katie Crissman
October 01 2020

Hyperhidrosis, a condition that causes excessive sweating, is currently recognized by doctors but is not a well understood disease. It is estimated that 2.8% of the US population suffers from hyperhidrosis which makes it a relatively common condition.[1] However, there are limited, and often invasive, treatment options available to those suffering from it. There is also a general lack of understanding about the etiology of the disease, and more research needs to be done in order to understand how it works so better treatments can be developed. There is currently no cure for hyperhidrosis, and further research needs to be done in order to get closer to finding one. There are two main types of hyperhidrosis, primary focal hyperhidrosis and secondary generalized hyperhidrosis. Primary focal hyperhidrosis is more common and usually starts during adolescence - it is this type that is less well understood. Secondary hyperhidrosis usually begins in adulthood and has a definitive causative factor. Most cases of secondary hyperhidrosis are caused by medications and other instances of the secondary hyperhidrosis are caused by disease or another biological process. Most future treatments are focused on alleviating the effects of primary focal hyperhidrosis, as secondary hyperhidrosis can usually be resolved by find out its cause. Research is going on to explore both medicinal treatments and devices that may be able to reduce sweat production.

Topical Anticholinergics

Currently, anticholinergics are available as an oral medication to treat hyperhidrosis. The problem with oral medication is that they affect the body systemically and often create unwanted side effects. Researchers are now trying to tell if anticholinergics can be applied topically to treat sweating at its source. Anticholinergics block the production of sweat so the idea is that applying it topically will do the same without the unpleasant side effects caused by an oral dose. A few small studies have been done but larger studies are needed in order to draw any conclusive evidence. Many of the topical anticholinergic formulations that have been studied use either glycopyrrolate or oxybutynin, two types of anticholinergics commonly used for hyperhidrosis. One small study using 1% glycopyrrolate cream (a type of anticholinergic) found that only 9 out of 35 patients had a 50% reduction in symptoms which does not sound promising. However, it has been suggested that a higher dose of the cream, like 2%, may be needed to see improvements. The participants also had very few adverse reactions which is a positive sign. Other studies have found more promising results using a 2% glycopyrrolate pad, one of which found that there was a mean of 61.8% reduction of sweating symptoms in the participants. Another anticholinergic called oxybutynin is also being studied in a topical form with limited but positive results.[1] There need to be larger, double-blind studies in the future but this may be a promising emerging therapy. Recently, a new product called Qbrexza, made by a company called Dermira, was relased. It is a wipe medicated with an anticholinergic. Qbrexza is marketing as being safe for children over the age of 9, so it is one of the few medical treatments available to children with hyperhidrosis.

Botox of the Future

Botox injections to treat palmar and plantar hyperhidrosis, as well as for axillary hyperhidrosis, have been effective treatments for those suffering with primary focal hyperhidrosis. Currently, a type of botox called onabotulinum toxin-A is FDA approved for the treatment of axillary hyperhidrosis. Unfortunately, the injections can be painful and invasive for the patients receiving them. It has been difficult to administer botulinum toxin directly onto the skin, in cream form, in the past because botulinum toxin is made up of fairly large molecules that have trouble crossing the skin barrier. As an improvement, a company called Revance Therapeutics Incorporated, has developed a transport peptide that allows the botox toxin to permeate skin without the need for an injection. This peptide is mixed with botulinum toxin and Cetaphil and applied to a person’s skin to create a botox cream that can potentially reduce sweating. So far, there has only been one small study done but it found that there was a 40% quantitative reduction in sweat which is a significant, positive finding.[1] Larger studies need to be conducted before the effectiveness of this treatment can be established but it is an encouraging future treatment option.

Devices that Reduce Sweating

Some devices can treat hyperhidrosis by heating up the skin and destroying sweat glands, thus reducing sweat production. One device that uses microwave technology is already FDA approved for the treatment of axillary hyperhidrosis, it is called MiraDry.[1] Several new devices are being developed to treat hyperhidrosis in a similar way but with different methods of heating the skin.[1]

Fractional Microneedle Radiofrequency (FMR) Treatment

Fractional microneedle radiofrequency treatment is a type of procedure that sends energy to the lower layer of the skin (reticular dermis) without causing injury to the top layer of skin (epidermis). The needles have electrode pins that form a closed circuit with the affected skin and can thus penetrate the surface. In the past FMR has been used to treat acne scars and wrinkles. In the trials that have been done (on axillary hyperhidrosis) it was found that after two months of treatments 60% of the participants had an HDSS (hyperhidrosis disease severity scale) or 1 or 2, which was a significant improvement.[1][2] More studies need to be done but this is a promising potential treatment that is less invasive and more convenient than the current localized permanent procedures for axillary hyperhidrosis available to patients.

Lasers

There has been some limited research on the use of lasers to treat specific problem areas on hyperhidrosis patients. Like the other devices, lasers heat the skin to damage eccrine glands so they produce less sweat. Trials using a long-pulsed 800 nm diode laser failed to identify a significant improvement. Another type of laser, called 1064-nm Nd-YAG, has shown promise for hyperhidrosis patients. It has specifically been tested on the axillary region. In one study 70.6% of patients in showed improvement on their patient’s global assessment while doctors reported that 80.6% of patients showed improvement according to the physician's global assessment. There have been a few studies showing that this type of laser show great potential in the future. Once more research is done this may be extremely beneficial to those suffering with underarm hyperhidrosis symptoms.[1]

Ultrasound For Hyperhidrosis

Ultrasound, which works by focusing ultrasonic energy at the end of a probe, is being studied to treat hyperhidrosis. Unlike the type of ultrasound used during a pregnancy, these are more invasive and used underneath the skin while patients are anesthetized.[1] The VASER ultrasound has been briefly studied in the treatment of axillary hyperhidrosis. It was found that it improved symptoms in patients for up to 6 months although longer-term results have not been obtained yet.[3] Another type of ultrasound, called intense focused ultrasound (IFUS) has been used proposed to treat hyperhidrosis but no studies have yet been published on the topic.[1] As more studies are done and more research is collected it will become more apparent whether ultrasound is a viable treatment option, but so far the results are encouraging.

Future Research

More research about hyperhidrosis is needed in order to develop more effective therapies and treat this uncomfortable condition. Specifically, it is important for researchers to figure out where the sweat glands are located and to better understand the physiology of hyperhidrosis as it is not currently well understood. There is currently no cure for hyperhidrosis, but with enough research and understanding one might be developed in the future. It is also imperative that more research is done to understand the pharmacology (how drugs impact) of hyperhidrosis and to develop new medications with less side effects that can treat the disorder.[1] Hyperhidrosis is hereditary, at least in part, so understanding how the genetics of the condition work may also lead to future developments.

Currently, many of the surgical treatments for primary focal hyperhidrosis are invasive or painful, but that will likely not be the case in the future. As more research is done it will become easier to manage hyperhidrosis with a doctor and there are several promising treatments in the works. Hyperhidrosis is getting more and more attention and as information spreads and technology is created the world will be a better place for those suffering from this debilitating condition.

Sources
  1. Pariser, D. M. (2014). Hyperhidrosis (4th ed., Vol. 32). Amsterdam: Elsevier Pub. Co., 2014. Retrieved
  2. Kim, M., Yong, J. S., Jungsoo, L., Young, J. K., & Sang, H. O. (2013). Efficacy of Fractional Microneedle Radiofrequency Device in the Treatment of Primary
  3. Axillary Hyperhidrosis: A Pilot Study. Dermatology, (227), 243-249. doi:10.1159/000354602
  4. Commons, G. W., & Lim, A. F. (2009). Treatment of Axillary Hyperhidrosis/Bromidrosis Using VASER Ultrasound. Aesthetic Plastic Surgery, 33, 312-323. doi:10.1007/s00266-008-9283-y
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Causes of Hyperhidrosis

How to Tell if I Have Hyperhidrosis

By Katie Crissman /

Are you dealing with excessive sweating? If you’re a super sweater, here's how you can tell whether your symptoms may be related to a condition called hyperhidrosis.

What is Hyperhidrosis?

Hyperhidrosis is a medical condition categorized by excessive sweating that isn’t related to temperature regulation. It affects roughly 3% of people and it’s very treatable.[1]

If you have hyperhidrosis then you may experience symptoms like: 

  • Sweating that specifically affects your hands, feet, underarms, face or groin.
  • You can’t find an environmental trigger for your sweat like heat.
  • Your sweat so much that it impacts your self confidence and interferes in your personal or work life.
  • You have to change clothes often due to sweat problems.[1]

You get the idea - hyperhidrosis causes sweating that’s disruptive and more or less constant. It’s important to know that there are two types of hyperhidrosis. They are called primary focal hyperhidrosis, and secondary generalized hyperhidrosis. In this article we are going to focus on the symptoms of primary focal hyperhidrosis.[1] 

However, if you have excessive sweating that doesn’t seem related to primary hyperhidrosis read our article on secondary generalized hyperhidrosis as it’s caused by underlying health conditions and it’s important to get them looked at. 

Back to primary hyperhidrosis! Here are some quick facts to know about the condition:

  • It’s categorized by profuse sweating in one or more specific areas of the body, the main areas affected are:
    • Hands
    • Feet 
    • Underarms 
    • Face
    • Groin
    • Breast
  • It typically starts in adolescence or during early adulthood. Sometimes kids can experience excessive hyperhidrosis as well.
  • It’s not a result of any other disease or disorder - the excessive sweating itself is the disorder.
  • Men are more likely to have it.
  • It tends to run in some families.
  • The sweating tends to be symmetrical on the body. For example, if your right hand sweats your left hand will too.
  • It’s treatable![1]

Factors to Consider When Self-Diagnosing Hyperhidrosis

If you can relate to our description of hyperhidrosis consider these factors when self diagnosing. The first thing to know is that you should consult a doctor! Specifically, a dermatologist who’s trained in dealing with hyperhidrosis. If you’re still interested in more information consider the following: 

1. Temperature and Weather

 

First and foremost, you should be cognizant of whether or not you sweat in response to high temperatures in your surrounding environment. Since sweat is produced primarily as a means to cool the body via thermoregulation, all people should sweat when the temperature is high. Typically, the higher the temperature, the more sweat produced to keep the body cool. However, the first sign of both primary and secondary hyperhidrosis is whether or not your body sweats even when the temperature is at a comfortable, or even cool, level. 

For those with hyperhidrosis, they have sweat glands that are overactive because they are receiving and reacting to too many signals from the spinal cord and brain. Due to the fact that these synaptic signals are sent regardless of temperature, gauging the temperature of the environment when sweating occurs is a strong indicator of potential hyperhidrosis.

2. Environmental Triggers

In addition to temperature, you should be aware of whether or not other environmental triggers are causing excessive sweating on a repeated basis. For example, situations that are anxiety producing like meeting new people, anticipating handshakes, preparing for major assignments or tests, and public speaking may prompt an individual’s hyperhidrosis to worsen. This is because hyperhidrosis and anxiety are closely related. 

When thinking of your own sweatiest moments, are they tied to a specific set of conditions? If so, you may have primary focal hyperhidrosis that is triggered by those specific conditions. 

However, an important distinction between hyperhidrosis and stress sweating related to anxiety must be made; just because someone sweats in a specific situation doesn’t mean they have hyperhidrosis. Most people will sweat a little before a business meeting, and many people find the idea of a public speech to be intimidating. 

The important distinction is to determine whether or not your body is producing sweat to aid with thermoregulation (i.e. keeping you cool and calm when you become a little worried before an event) or producing sweat at an excessive and uncontrollable rate. 

3. Timing of Your Sweat

The third factor to evaluate in order to tell if a person’s sweating is indicative of hyperhidrosis is the length of time a person has been experiencing excessive sweating. If you’ve been sweating excessively since adolescence or young adulthood it’s a sign you may have primary hyperhidrosis. If it just started suddenly later in life it’s less likely to be secondary hyperhidrosis. 

If you think you might have hyperhidrosis there are many ways to manage your sweat and there are several treatments you can try. A great starting place is finding a good antiperspirant - we recommend Carpe antiperspirant lotion. They have products tailored to each specific part of your body and their special formula is gentle on skin.

Are you still curious about whether you have hyperhidrosis? Take this quiz.

Sources
  1. Pariser, D. M. (2014). Hyperhidrosis (4th ed., Vol. 32). Amsterdam: Elsevier Pub. Co., 2014. Retrieved from https://www.elsevier.com/books/hyperhidrosis-an-issue-of-dermatologic-clinics/pariser/978-0-323-32607-0 
  2. Kamudoni, P., Mueller, B., Halford, J., Schouveller, A., Stacey, B., & Salek, M. (2017, June 8). The impact of hyperhidrosis on patients' daily life and quality of life: A qualitative investigation. Retrieved May 21, 2018, from https://hqlo.biomedcentral.com/articles/10.1186/s12955-017-0693-x
  3. MiraMar Labs, O'Shaughnessy, K., & Melkerson, M. (2011). 510(k) Summary. Division of Surgical, Orthopedic And Restorative Devices. Retrieved May 23, 2018, from https://www.accessdata.fda.gov/cdrh_docs/pdf10/K103014.pdf.
    Body Areas Affected by Hyperhidrosis

    How to Cure Sweaty Hands Permanently at Home

    By Daniel McCarthy /

    How to Cure Sweaty Hands Permanently at Home 

    Scenario 1: You’re invited into the office, confident you will land the job. You’ve prepared, you’re highly qualified, you have absolutely nothing to worry about. You walk in and confidently reach out to shake the CEOs hand. But then, your confidence turns to dread as the CEO pulls her hand back, wet with your sweat. 

    Scenario 2: You’re at home, playing video games with your friends and absolutely dominating. They get so upset, they tell you to take a break to let another friend play. But there’s another problem... nobody wants to use your controller after you finish. Despite your domination, your palmar hyperhidrosis (excessively sweaty hands) has taken center stage. 

    Do these scenarios sound familiar? Wondering how to cure sweaty hands permanently? Although you may not have had these exact things happen to you, your sweaty hands likely have caused something similar and you’re looking for a home remedy. To stop sweating these situations, let’s talk about how to cure sweaty hands permanently at home. 

    One of the best ways to cure sweaty hands at home is actually not related to the hands at all. Instead, working on reducing anxiety can have immensely positive results on how to cure sweaty hands permanently naturally. There are many root causes of anxiety, and some or many may be related to your hyperhidrosis. Likewise, it is easier said than done to reduce anxiety. But there are also many ways to work on reducing anxiety that are worth a try. One interesting way to reduce anxiety, and in turn, sweaty hands, is to be grateful. Specifically, Petrocchi and Couyoumdjian found that “grateful people experience less anxiety mostly because they are able to encourage and be compassionate and reassuring toward themselves when things go wrong in life” [1]. Other ways include stepping outside for a walk, drinking tea, or even distracting yourself. In general, starting with anxiety reduction not only can help with how to cure sweaty hands, but also your wellbeing in general. 

    Another great way to cure sweaty hands at home permanently is to reduce consumption of coffee and alcohol. Now you may be reading this and thinking “Hey, those are all my favorite things! I’m done with this article!”. And while I wholeheartedly agree and enjoy coffee and alcohol myself, consumption in moderation is key, especially with hyperhidrosis. Caffeine, for example, activates part of the brain that is already a main part in causing hyperhidrosis symptoms. Instead of giving it up, try to reduce consumption to under 200 mg or add in decaf to your routine. Alcohol can affect hyperhidrosis in a similar manner, but like coffee, 1-2 glasses of alcohol may be okay. When figuring out how to cure sweaty hands permanently naturally, it is important to find a balance of coffee, alcohol, and managing your hyperhidrosis. And remember to always drink responsibly, in moderation. 

    Tackling how to cure sweaty hands permanently, naturally, and at home may require more than behavioral changes we’ve talked about so far. Luckily, there are other great remedies you can try at home! First, finding the right antiperspirant is of paramount importance, especially appropriate antiperspirant for hands. Another possible over the counter option is anti-sweat wipes. If neither of these work for you, another option to cure your sweaty hands permanently is to buy your very own iontophoresis machine for at-home use. This machine delivers mild electrical currents to your hands (or other affected body part) while submerged in water. A combination of these treatments may have your hands feeling less clammy in no time! 

    Ultimately, your palmar hyperhidrosis may not be treatable at home and permanently, but these recommendations may help alleviate some of your symptoms. If symptoms persist, consult a medical professional for further assistance with how to cure sweaty hands. 



    Sources

    Sources

    1. Nicola Petrocchi & Alessandro Couyoumdjian (2016) The impact of gratitude on depression and anxiety: the mediating role of criticizing, attacking, and reassuring the self, Self and Identity, 15:2, 191-205, DOI: 10.1080/15298868.2015.1095794
    Causes of Hyperhidrosis

    Everything you need to to know about Hyperhidrosis (or Excessive Sweat)

    By Chris Reid /

    WHAT IS HYPERHIDROSIS?

    Hyperhidrosis, or excessive sweating, is basically when you sweat beyond comfort. People with hyperhidrosis just have overactive sweat glands. 

    The medical definition is sweat that is produced in excess of what is necessary for thermoregulation (the ability to maintain a healthy temperature.

    Sweating is a perfectly natural and necessary function the body uses to cool itself down. We need to sweat to live, however, with hyperhidrosis, you’ll sweat even when your body isn’t overheating.[1] 

    SIGNS YOU MAY HAVE HYPERHIDROSIS: 

    • When dressing, you take into account how your clothes will be affected by sweat and whether they will show sweat stains. 
    • You are always aware of your environment and whether or not you can influence the temperature. 
    • You've hesitated to shake someone's hand. 
    • You tailor your routine to take in account a need for reapplying your deodorant. 
    • You worry about taking off you shoes in front of others. 
    • You leave a sweat trail. 
    • Noticeable sweat even when you aren't working out or overheated. 

    WE DON'T JUST SWEAT UNDER THE ARMS: 

    All can be affected: 

    • Feet
    • Hands
    • Groin
    • Chest/Breasts
    • Thighs
    • Buttocks
    • Face
    • Scalp

    You could have sweat in just one of these areas, or like the lucky few experience full body excessive sweating. 

    Hands, feet, and underarms are the parts of the body that are most likely to be affected by hyperhidrosis.[3]

    People who suffer from hyperhidrosis have the same number and size of sweat glands as people who don’t have the condition. Their sweat glands are just overactive.[1]

    THERE ARE SOLUTIONS: 

    Good news, you don't have to live with uncomfortable sweat.

    SOME OPTIONS: 

    If you are interested in medical solutions, you can book an appointment with your dermatologist and learn how to manage hyperhidrosis with a dermatologist.[3]

    THERE ARE TWO MAIN FORMS OF HYPERHIDROSIS

    The vast majority of people will either have primary focal hyperhidrosis or secondary generalized hyperhidrosis. 

    Primary Focal Hyperhidrosis

    Primary Focal Hyperhidrosis (PFH) is by far the most common type, affecting up to 90 percent of people who have hyperhidrosis. 

    People with primary focal hyperhidrosis only sweat in particular areas like the hands, feet, armpits, face, and groin.

    Sweat will occur on both sides of the body in the same place and often in more than one area — like both hands and feet. [3]

    Symptoms usually begin in childhood or adolescence and tend to last for a person’s entire lifetime. There is evidence that primary focal hyperhidrosis is hereditary, meaning it often runs in families.[3]

    Secondary Generalized Hyperhidrosis

    While primary focal hyperhidrosis appears to be something you’re born with, secondary generalized hyperhidrosis (SGH) is a condition that shows up during adulthood. Think of SGH as an uninvited guest who arrives on your doorstep with no warning. [3]

    When someone has secondary hyperhidrosis the biggest problem isn’t the hyperhidrosis – it’s the disease or condition that might be causing it. [3]

    The source of this type of hyperhidrosis can also be a medication. Many common medications can cause hyperhidrosis as a side effect.[3]

    Unlike primary focal hyperhidrosis, the sweating from secondary hyperhidrosis tends to occur all over the body. This is a telltale sign of the condition.[3]

    Unlike primary hyperhidrosis, this condition doesn’t have to be permanent. If the instigating condition is found and treated, it can fix the hyperhidrosis. It may take a little work.[3]

    If you are concerned that your hyperhidrosis might have an underlying cause, schedule an appointment to talk to your doctor and find out.[3]

    THE IMPACTS OF HYPERHIDROSIS

    While hyperhidrosis isn’t particularly dangerous physically, it can be embarrassing.[3]

    Unfortunately, hyperhidrosis is more serious than just uncomfortable sweating.

    Up to a third of people who deal with excessive sweating from hyperhidrosis say that they are constantly bothered by their sweating.

    • 75% of respondents reported that hyperhidrosis negatively impacted their social, emotional, and mental health.[4] 
    •  Hyperhidrosis and anxiety often go hand in hand.[3] 

    HOW COMMON IS HYPERHIDROSIS?

    • 3% of the US population struggles with hyperhidrosis. In other countries the percentage of the population that has it is even higher.[3] 

    Because hyperhidrosis is such an embarrassing and overlooked condition, many individuals avoid reporting the issue to their doctor. This means that the number of people who have hyperhidrosis might even be higher than we currently think.[3]

    What Causes Hyperhidrosis?

    Doctors don’t truly understand what causes primary focal hyperhidrosis yet. One theory is that particular nerves that control the amount of sweat overreact or malfunction. That malfunction can cause the excessive sweating that can be life-changing for those who suffer from it.[7]

    Since hyperhidrosis affects so many people, researchers are now shifting into full gear to discover the causes of excessive sweating so they can develop better treatments. Future treatments and research for hyperhidrosis are being developed more rapidly than ever before.[3]

    What Conditions Can Cause Secondary Generalized Hyperhidrosis?

    Many diseases and medical conditions can cause hyperhidrosis. However, just because you have one of the conditions listed below this paragraph doesn’t mean you’ll develop hyperhidrosis.

    Here are some of the more common conditions that may be causing the hyperhidrosis you have developed as an adult.

    • A febrile illness
    • Menopause
    • Hyperthyroidism
    • Heart failure
    • Diabetes
    • Frostbite
    • Alcoholism - Alcohol can cause excessive sweating when someone is intoxicated, withdrawing, or in someone with an intolerance.
    • Gout
    • Lymphoma and some other cancers and tumors.
    • Obesity
    • Pregnancy
    • Parkinson’s disease
    • Rheumatoid arthritis
    • Stroke[3]

    There are also several types of common medications that cause hyperhidrosis as a side effect. So, if you are on medication and you begin experiencing new or increased amounts of sweating mention it to your doctor. Some of these medications include antidepressants, painkillers, blood pressure medications and many others.a [3]

    If you think you might have secondary generalized hyperhidrosis it is very important that you speak to a doctor. Many of the things that cause it can be resolved, and it could be a sign of a more serious problem. Don’t panic, but it is wise to look into the reason you are sweating more.

    What Are the Treatments for Primary Focal Hyperhidrosis?

    If you are diagnosed with primary focal hyperhidrosis, there are many things you can do.These are the existing treatments for hyperhidrosis, but new treatments are currently being explored by scientists:

    • Antiperspirants:There are many over-the-counter antiperspirants that can be very useful when trying to curb sweat. If a regular antiperspirant isn’t cutting it for you, ask your doctor to write a prescription for a stronger one. You can apply antiperspirant to places other than just your underarms. Use it on your hands, hairline, or feet as well. There are even antiperspirants for the face and groin that are made specifically for sensitive areas.
    • An Iontophoresis machine:This medical device sends low-voltage currents into a pan of water where your hands or feet are sitting. The electricity can lessen the activity of your sweat glands, at least for a while. However, it can take up to 10 sessions with the iontophoresis machine to deactivate your sweat glands. You may need to use this machine up to three times a week in the beginning and one treatment can take up to 40 minutes. Although iontophoresis as a treatment for palmar and plantar hyperhidrosis may give your hands and feet a much needed break, the iontophoresis machine is anything but convenient. Iontophoresis really does work, but patients have to be willing to keep up with a regular treatment regimen for it to work successfully.
    • Botox:If other treatments aren’t enough in your, you might need Botox injections. Botox can be particularly useful for axillary hyperhidrosis, but botox can also be a treatment for palmar and plantar hyperhidrosis. Botox can provide up to 6 months of reduced sweating. If you’re going to pursue this route, you should look for someone who is experienced at doing Botox injections in the underarms to ensure the right area is targeted.
    • Anticholinergics:A few oral medications can for hyperhidrosis can reduce the amount of sweat you produce by stopping your sweat glands from working. Most commonly patients are prescribed anticholinergics like glycopyrrolate or oxybutynin as a treatment for hyperhidrosis. These medications also have several side effects, including heart palpitations, blurry vision, and dry mouth.
    • ETS Surgery:An endoscopic thoracic sympathectomy (ETS) is a surgical treatment for primary focal hyperhidrosis. It is an operation where an individual actually has the nerve endings that transfer sensory information to the sweat glands destroyed. Since no known successful reversal of an ETS surgery has ever been recorded, this option isn’t usually on the table unless the other treatments have failed. As with any surgery, it can be risky. There is also a type of surgery called an endoscopic lumbar sympathectomy which is used to treat plantar hyperhidrosis, but this surgery can be very dangerous and is almost never recommended.[3]

    Defeating Hyperhidrosis

    Undoubtedly, hyperhidrosis can be a hard condition to cope with. Until recently, the lack of research into hyperhidrosis had made hyperhidrosis difficult to manage. Thankfully, however, new treatments and awareness has made hyperhidrosis much easier to handle. Keep trying treatments until you find what works for you and remember that you are not alone in suffering with this condition. It’s just a matter of figuring out what you can do to control your sweat instead of your sweat controlling you!

    Sources
      1. MedicineNet Medical Journal. (2016, May 13). Definition of Hyperhidrosis. Retrieved May 14, 2018, from https://www.medicinenet.com/script/main/art.asp?articlekey=16272
      2. Diaphoresis: What causes excessive sweating? (n.d.). Retrieved May 20, 2020, from https://www.medicalnewstoday.com/articles/321663#overview
      3. Pariser, D. M. (2014). Hyperhidrosis (4th ed., Vol. 32). Amsterdam: Elsevier Pub. Co., 2014. Retrieved from https://www.elsevier.com/books/hyperhidrosis-an-issue-of-dermatologic-clinics/pariser/978-0-323-32607-0
      4. Lenefsky, M., & Rice, Z. P. (2018). Hyperhidrosis and Its Impact on Those Living With It. AJMC. Retrieved from https://www.ajmc.com/journals/supplement/2018/hyperhidrosis-managed-markets-update-treatments/hyperhidrosis-and-its-impact--on-those-living-with-it

    Nordqvist, C. (2017, December 21). Hyperhidrosis: Symptoms, causes, diagnosis, and treatment. Retrieved May 14, 2018, from https://www.medicalnewstoday.com/articles/182130.php

    Doolittle, James, et al. “Hyperhidrosis: an Update on Prevalence and Severity in the United States.” Archives of Dermatological Research, vol. 308, no. 10, 2016, pp. 743–749., doi:10.1007/s00403-016-1697-9. Retrieved from https://pubmed.ncbi.nlm.nih.gov/27744497/

    Huddle, J. R. (2014). Hyperhidrosis: Causes, Treatment Options and Outcomes. New York, NY: Nova Science. Retrieved from https://www.bookdepository.com/Hyperhidrosis-Janine-R-Huddle/9781633215160

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